Making sense of socially enhanced aggression in the brains of mice

When male animals spend time around other males of the same species, subsequent aggressive behavior tends to be amplified—this type of priming is known as social instigation. However, the pathway in the brain that leads to this increased aggression was, until recently, relatively unknown. In a study published in Nature Communications, researchers from the University […]

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Shrinking liver cancer tumors before transplant yields excellent outcomes, researchers report

Treating liver cancer tumors to shrink them in order to allow the patient to qualify for a liver transplant leads to excellent 10-year post-transplant outcomes, according to new Mount Sinai research published in JAMA Surgery. The results validate current national policies around transplant eligibility. Selection of patients with hepatocellular carcinoma (HCC), the most common form […]

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Bolstering the reliability of epigenetic clocks

Epigenetic clocks are powerful biomarkers based on DNA methylation that were developed to track aging in population studies, clinical trials, and personal health applications. Intended to measure biological age, they strongly predict age-related morbidity and mortality along with other aspects of health. Now, scientists from Yale School of Medicine, in collaboration with international research colleagues, […]

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Asthma medication not working? Try another

People who supplement rescue inhalers with a second asthma medication sometimes get little relief at first, but there’s good news: Those who keep trying different options often find a medication that works, according to Rutgers researchers. The researchers analyzed data from 2,025 patients who used any of six FDA-approved severe asthma treatments known as “biologics” […]

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New study reveals large differences in types of contraceptives used across regions and age groups

Expanding access to contraception is linked to women’s social and economic empowerment and better health outcomes and is a key goal of international initiatives and is a Sustainable Development Goal (SDG) indicator. Contraception use is also associated with reductions in maternal and neonatal mortality by preventing unintended pregnancies. By allowing women to plan childbearing, contraception […]

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No evidence that ‘overlapping surgery’ to reduce hospital waiting lists will increase number of operations

Overlapping surgery, in which a single senior surgeon operates across two parallel operating theaters and anesthetists induce anesthesia and junior surgeons commence and complete the operation, has been discussed as a potential route to reducing hospital waiting lists in this pandemic era in which many patients are expected to face extensive delays of months or […]

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